Pentagalloylglucose

CAS: 14937-32-7

Ref. TM-T3794

Product Information

• Name: Pentagalloylglucose
• Synonyms: Penta-O-galloyl-β-D-glucose, 1,2,3,4,6-O-Pentagalloylglucose, 1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose, 1,2,3,4,6-O-Pentagalloylglucose, 1,2,3,4,6-Penta-O-Galloyl-B-D-Glucopyranose, 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucopyranose, 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucopyranoside, 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucose, 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucoside, 1,2,3,4,6-Penta-O-galloyl-β-glucopyranose, 1,2,3,4,6-Penta-O-galloylglucose, 1,2,3,4,6-Pentagalloyl-β-<span class="text-smallcaps">D</span>-glucopyranose, 1,2,3,4,6-Pentagalloyl-β-<span class="text-smallcaps">D</span>-glucopyranoside, 1,2,3,4,6-Pentagalloyl-β-<span class="text-smallcaps">D</span>-glucose, 1,2,3,4,6-Pentagalloylglucose, 1,2,3,4,6-pentakis-O-(3,4,5-trihydroxybenzoyl)-beta-D-glucopyranose, Db 03208, G 7548, Gallic acid, pentaester with β-<span class="text-smallcaps">D</span>-glucopyranose, Gallotannin 15, Glucopyranose, pentagallate, β-<span class="text-smallcaps">D</span>-, PGG, Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucopyranose, Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucose, Penta-O-galloylglucose, Penta-Ortho-Galloylglucose, Pentagalloyl Glucose, Pentagalloyl-<span class="text-smallcaps">D</span>-glucose, beta-penta-O-galloyl-glucose, β-1,2,3,4,6-Pentagalloylglucose, β-<span class="text-smallcaps">D</span>-Glucopyranose, 1,2,3,4,6-pentakis(3,4,5-trihydroxybenzoate), β-<span class="text-smallcaps">D</span>-Glucopyranose, pentakis(3,4,5-trihydroxybenzoate)
• CAS: 14937-32-7

Description

1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses potent anti-proliferative and anti-invasive effects, it also has inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity. 3. PGG may serve as a model for the development of new types of anti-diabetic and anti-metabolic syndrome therapeutics. 4. 1, 2, 3, 4, 6-Penta- O -galloyl-β- d -glucose has vasodilatory and anti-inflammatory effects, it dilates vascular smooth muscle and suppresses the vascular inflammatory process via endothelium-dependent nitric oxide (NO)/cGMP signaling. 5. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose can decrease the level of extracellular hepatitis B virus (HBV) (IC5, 1. microg/ml) in a dose-dependent manner, it also can reduce the HBsAg level by 25% at a concentration of 4 microg/ml; the gallate structure of PGG may play a critical role in the inhibition of anti-HBV activity, suggests that PGG could be a candidate for developing an anti-HBV agent. 6. 1, 2, 3, 4, 6-Penta-O-galloyl-β-D-glucose has anti-parasitic activity, displays an EC5 value of 67 μM, at least 6.6-fold more effective than the standard drug benznidazole against trypomastigote forms of T. cruzi.

• Brand: Targetmol

Chemical properties

• Molecular weight: 940.68
• Formula: C₄₁H₃₂O₂₆
• Purity: 99.58%
• Color/Form: Yellow Powder