sn-Glycero-3-phosphocholine

CAS: 28319-77-9

Ref. TM-T4439

Product Information

• Name: sn-Glycero-3-phosphocholine
• Synonyms: Choline Alfoscerate, Glycerophosphocholine, Glycerophosphorylcholine, Alpha-GPC, Choline glycerophosphate, L-α-GPC, (2R)-2,3-dihydroxypropyl 2-(trimethylammonio)ethyl phosphate, (2S)-2,3-dihydroxypropyl 2-(trimethylammonio)ethyl phosphate, <span class="text-smallcaps">L</span>-α-GPC, <span class="text-smallcaps">L</span>-α-Glycerophosphocholine, <span class="text-smallcaps">L</span>-α-Glycerophosphorylcholine, <span class="text-smallcaps">L</span>-α-Glycerylphosphorylcholine, Alpha GPC,choline alfoscerate, Brezal, Cereton, Cholicerin, Choline Alfoscerate, Choline Glycerophosphate, Choline alphoscerate, Choline, hydroxide, 2,3-dihydroxypropyl hydrogen phosphate, inner salt, <span class="text-smallcaps">D</span>-, Cholitiline, Delecit, Ethanaminium, 2-[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, hydroxide, inner salt, (R)-, Ethanaminium, 2-[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt, (R)-, Ethanaminium, 2-[[[(2R)-2,3-dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt, GPC, Gliatilin, Glycerol 3-phosphocholine, Glycerol 3-phosphorylcholine, Glycerol phosphorylcholine, Glycerophosphocholine, Glycerophosphoric acid choline ester, Glycerophosphorylcholine, Glyceryl 3-phosphorylcholine, Glycerylphosphocholine, Glycerylphosphorylcholine, L-ALPHA-Glycerophosphoryl choline, Nichiyu GPC 85R, O-(sn-glycero-3-Phosphoryl)-choline, sn-glycero-3-Phosphocholine, sn-glycero-3-Phosphorylcholine, α-Glycerophosphorylcholine, α-Glycerylphosphorylcholine
• CAS: 28319-77-9

Description

sn-Glycero-3-phosphocholine (Choline glycerophosphate) is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have a potential for the treatment of Alzheimer's disease and dementia. sn-Glycero-3-phosphocholine rapidly delivers choline to the brain across the blood-brain barrier and is a biosynthetic precursor of the acetylcholine neurotransmitter. It is a non-prescription drug in most countries due to its Generally Recognised As Safe (GRAS) status [1]. Studies have investigated its efficacy for cognitive disorders including stroke and Alzheimer's disease. An Italian multicentre clinical trial on 2, 044 patients suffering from recent stroke were supplied Glycerylphosphorylcholine in doses of 1, 000 mg/day for 28 days and 400 mg three times per day for the five ensuing months. The trial confirmed the therapeutic role of alpha-GPC on the cognitive recovery of patients based on four measurement scales, three of which reached statistical significance [2].

• Brand: Targetmol

Chemical properties

• Molecular weight: 257.22
• Formula: C₈H₂₀NO₆P
• Purity: 98.53%
• Color/Form: Solid