(R)-5-Oxopyrrolidine-2-carboxylic acid

CAS: 4042-36-8

Ref. TM-T4814

Product Information

• Name: (R)-5-Oxopyrrolidine-2-carboxylic acid
• Synonyms: D-Pyroglutamic acid, (R)-(+)-2-Pyrrolidone-5-carboxylic acid, (+)-2-Pyrrolidone-5-carboxylic acid, (+)-<span class="text-smallcaps">D</span>-Pyroglutamic acid, (+)-Pyroglutamic acid, (2R)-2-Carboxy-5-pyrrolidinone, (2R)-5-Oxopyrrolidine-2-carboxylic acid, (R)-(+)-2-Pyrrolidinone-5-carboxylic acid, (R)-(+)-2-Pyrrolidone-5-carboxylic acid, (R)-(+)-5-Oxopyrrolidine-2-carboxylic acid, (R)-5-Oxoproline, (R)-Pyroglutamic acid, 2-Oxopyrrolidine-1-Carboxylic Acid, 5-Oxo-<span class="text-smallcaps">D</span>-proline, <span class="text-smallcaps">D</span>-2-Pyrrolidone-5-carboxylic acid, <span class="text-smallcaps">D</span>-Pidolic acid, <span class="text-smallcaps">D</span>-Proline, 5-oxo-, <span class="text-smallcaps">D</span>-Pyrrolidinonecarboxylic acid, <span class="text-smallcaps">D</span>-Pyrrolidonecarboxylic acid, D-5-Pyrrolidone-2-carboxylic acid, D-Pyroglutamic acid, H-D-Pyr-OH, Proline, 5-oxo-, <span class="text-smallcaps">D</span>-
• CAS: 4042-36-8

Description

(R)-5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) is a cyclic derivative of glutamic acid, physiologically present in mammalian tissues. It has been shown that PCA releases GABA from the cerebral cortex and displays anti-anxiety effects in a simple approach-avoidance conflict situation in the rat. In clinical pharmacology experiments, PCA significantly shortens the plasma half-life of ethanol during acute intoxication.

• Brand: Targetmol

Chemical properties

• Molecular weight: 129.11
• Formula: C₅H₇NO₃
• Purity: 98%
• Color/Form: Solid
• InChI: InChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)
• InChI key: InChIKey=ODHCTXKNWHHXJC-UHFFFAOYSA-N
• SMILES: O=C1CCC(C(=O)O)N1