Tetrahydroxystilbene-2-O-β-D-glucoside

CAS: 55327-45-2

Ref. TM-T4956

Product Information

• Name: Tetrahydroxystilbene-2-O-β-D-glucoside
• Synonyms: tetrahydroxyl diphenylethylene-2-o-gluco, EH-201, 2,3,5,4'-Tetrahydroxytoluylene-2-Beta-D-Glucoside, 2,3,5,4′-Tetrahydroxyldiphenylethylene 2-O-β-<span class="text-smallcaps">D</span>-glucoside, 2,4-Dihydroxy-6-[2-(4-hydroxyphenyl)ethenyl]phenyl β-<span class="text-smallcaps">D</span>-glucopyranoside, β-<span class="text-smallcaps">D</span>-Glucopyranoside, 2,4-dihydroxy-6-[2-(4-hydroxyphenyl)ethenyl]phenyl
• CAS: 55327-45-2

Description

Tetrahydroxystilbene-2-O-β-D-glucoside (EH-201) is a low MW inducer of erythropoietin. Tetrahydroxystilbene-2-O-β-D-glucoside induces expression of erythropoietin, PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo, Tetrahydroxystilbene-2-O-β-D-glucoside treatment restores memory impairment, as assessed by the passive avoidance test, in SD, Aβ and KA mouse models. In the hippocampus of mice given Tetrahydroxystilbene-2-O-β-D-glucoside in their diet, levels of erythropoietin, PGC-1α and haemoglobin were increased. Treatment with Tetrahydroxystilbene-2-O-β-D-glucoside might be a therapeutic strategy for memory impairment in neurodegenerative disease, physiological ageing or traumatic brain injury.

• Brand: Targetmol

Chemical properties

• Molecular weight: 406.38
• Formula: C₂₀H₂₂O₉
• Purity: 98%
• Color/Form: Solid
• InChI: InChI=1S/C20H22O9/c21-9-15-16(25)17(26)18(27)20(28-15)29-19-11(7-13(23)8-14(19)24)4-1-10-2-5-12(22)6-3-10/h1-8,15-18,20-27H,9H2/b4-1+/t15-,16-,17?,18-,20?/m1/s1
• InChI key: InChIKey=JAYVHSBYKLLDJC-YXBFRYHSSA-N
• SMILES: OC[C@H]1OC(Oc2c(O)cc(O)cc2/C=C/c2ccc(O)cc2)[C@H](O)C(O)[C@@H]1O