DDD107498 succinate
CAS: 2444781-71-7
Ref. TM-T5404
50mg | Discontinued | ||
100mg | Discontinued | ||
200mg | Discontinued |
Product Information
- MMV121, M 5717, DDD498
DDD107498 succinate (DDD-498 succinate) is a potent and orally active antimalarial agent with good pharmacokinetic properties and an acceptable safety profile. DDD107498 succinate inhibits multiple life-cycle stages of the parasite with an EC 50 of 1 nM against P. falciparum 3D7. DDD107498 succinate inhibits protein synthesis by targeting eEF2/CaMKIII, with an EC 50 of 2 nM for WT- Pf eEF2 [1].