MPZ Protein, Human, Recombinant (His)
Ref. TM-TMPJ-00913
| 1mg | 2,591.00 € | ||
| 10µg | 185.00 € | ||
| 50µg | 535.00 € | ||
| 500µg | 1,803.00 € |
Product Information
- Myelin Peripheral Protein, Myelin Protein P0, MPZ, Myelin Protein Zero, MPP
Myelin Protein P0 (MPZ) is a single-pass type I membrane glycoprotein which belongs to the myelin P0 protein family. MPZ contains one Ig-like V-type (immunoglobulin-like) domain, absent in the central nervous system. MPZ is a major component of the myelin sheath in peripheral nerves. It is postulated that MPZ is a structural element in the formation and stabilisation of peripheral nerve myelin, holding its characteristic coil structure together by the interaction of its positively-charged domain with acidic lipids in the cytoplasmic face of the opposed bilayer, and by interaction between hydrophobic globular of adjacent extracellular domains. Defects in MPZ associated with Charcot-Marie-Tooth disease and Dejerine-Sottas disease.
Chemical properties
Technical inquiry about: TM-TMPJ-00913 MPZ Protein, Human, Recombinant (His)
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