PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
Ref. TM-TMPK-00422
1mg | 5,169.00 € | ||
100µg | 799.00 € | ||
500µg | 3,089.00 € |
Product Information
- PDGFR-2, PDGF R β/CD140b, PDGFR1, CD140B, PDGFR, PDGF R β, JTK12, PDGF R beta, PDGFR-β, PDGFRB
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF isoforms with high affinity, PDGF R beta binds PDGF-BB only with high-affinity. PDGF R plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.
Chemical properties
Technical inquiry about: TM-TMPK-00422 PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
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