PDGF R beta/CD140b Protein, Canine, Recombinant (His)
Ref. TM-TMPK-01050
| 1mg | 3,098.00 € | ||
| 100µg | 490.00 € | ||
| 500µg | 1,859.00 € |
Product Information
- JTK12, PDGF R β, PDGFR-β, PDGFR, PDGFRB, PDGF R beta, PDGF R β/CD140b, PDGFR1, CD140B, PDGFR-2
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF isoforms with high affinity, PDGF R beta binds PDGF-BB only with high-affinity. PDGF R plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.
Chemical properties
Technical inquiry about: TM-TMPK-01050 PDGF R beta/CD140b Protein, Canine, Recombinant (His)
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