IGFBP-3R Protein, Mouse, Recombinant (hFc)
Ref. TM-TMPK-01157
| 1mg | 2,942.00 € | ||
| 100µg | 466.00 € | ||
| 500µg | 1,756.00 € |
Product Information
- GFBP3R, IGFBP-3R, TMEM219, LOC124446
Insulin-like growth factor-binding protein-3 (IGFBP-3) is a multifunctional protein known for modulating mitogenic and metabolic actions of IGFs as well as exerting a variety of biological actions not involving IGF. IGFBP-3 inhibits airway inflammation and hyper-responsiveness via an IGF-independent mechanism that involves activation of IGFBP-3R signaling and cross-talk with NF-κB signaling. The IGFBP-3/IGFBP-3R system therefore plays a pivotal role in the pathogenesis of asthma and can serve as a newly identified potential therapeutic target for this debilitating disease.
Chemical properties
Technical inquiry about: TM-TMPK-01157 IGFBP-3R Protein, Mouse, Recombinant (hFc)
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