Notch 3 Protein, Human, Recombinant (His)
Ref. TM-TMPK-01396
| 1mg | 3,085.00 € | ||
| 100µg | 488.00 € | ||
| 500µg | 1,851.00 € |
Product Information
- NOTCH3, CADASIL, Notch-3, Notch homolog 3
Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular domain of transmembrane ligands Jagged, Delta, and Serrate expressed on the surface of a neighboring cell. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.
Chemical properties
Technical inquiry about: TM-TMPK-01396 Notch 3 Protein, Human, Recombinant (His)
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