Arotinoid Ethyl Ester

CAS: 71441-09-3

Ref. TR-A040210

Product Information

• Name: Arotinoid Ethyl Ester
• Synonyms: Benzoic acid, 4-​[(1E)​-​2-​(5,​6,​7,​8-​tetrahydro-​5,​5,​8,​8-​tetramethyl-​2-​naphthalenyl)​-​1-​propen-​1-​yl]​-​, ethyl ester, Benzoic acid, 4-[(1E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]-, ethyl ester (9CI), Benzoic acid, 4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]-, ethyl ester, (E)-, Arotinoid, Ro 13-6298, (E)-4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid ethyl ester, Arotinoid ethyl ester, Benzoic acid, 4-[(1E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propen-1-yl]-, ethyl ester, Benzoic acid, 4-[(1E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]-, ethyl ester, Ro-136298, ethyl 4-[(1E)-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]benzoate, ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid, 乙基-P-((E)-2-(5,6,7,8-四氢-5,5,8,8-甲基-2-萘基)-1-丙烯基)苯甲酸
• CAS: 71441-09-3

Description

Applications Arotinoid ethyl ester is a retinoid with a similar structure to vitamin A (R252000), and inhibits human epidermal keratinocyte RNase P activity, as well as tRNA biogenesis.
References Liao, W.; et al.: Zhongguo Linchuang Yaolixue Yu Zhiliaoxue, 19, 112 (2014); Papadimou, E.; et al.: Biol. Chem., 384, 457 (2003); Papadimou, E.; et al.: Skin Pharmacol. Physiol., 13, 345 (2000).

• Brand: TRC

Chemical properties

• Molecular weight: 376.531
• Formula: C₂₆H₃₂O₂
• Color/Form: Beige Solid
• InChI: InChI=1S/C26H32O2/c1-7-28-24(27)20-10-8-19(9-11-20)16-18(2)21-12-13-22-23(17-21)26(5,6)15-14-25(22,3)4/h8-13,16-17H,7,14-15H2,1-6H3/b18-16+
• InChI key: InChIKey=NULUAKSYPPSJCO-FBMGVBCBSA-N
• SMILES: CCOC(=O)c1ccc(/C=C(\C)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1