N-​[5-​(Acetylamino)​-​2-​hydroxyphenyl]​-​N-​(4-​hydroxyphenyl)​acetamide

CAS: 98966-17-7

Ref. TR-A161245

Product Information

• Name: N-​[5-​(Acetylamino)​-​2-​hydroxyphenyl]​-​N-​(4-​hydroxyphenyl)​acetamide
• Synonyms: Acetaminophen Dimer Impurity, Paracetamol Dimer 3, Acetaminophen Impurity B
• CAS: 98966-17-7

Description

Impurity Acetaminophen Impurity B
Applications N-​[5-​(Acetylamino)​-​2-​hydroxyphenyl]​-​N-​(4-​hydroxyphenyl)​acetamide is an impurity of Acetaminophen (A161220), which is an analgesic and antipyretic (1,2,3,4). N-​[5-​(Acetylamino)​-​2-​hydroxyphenyl]​-​N-​(4-​hydroxyphenyl)​acetamide may be a useful reagent to investigate mechanisms related to liver and kidney damage from acetaminophen. Acetaminophen Impurity B.
References (1) Potter, D. W. and Hinson, J. A.: Drug Metab Rev. 20, 341 (1989) (2) Potter, D. W. and Hinson, J. A.: J. Biol. Chem. 260, 12174 (1985) (3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)(4) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)

• Brand: TRC

Chemical properties

• Molecular weight: 300.31
• Formula: C₁₆H₁₆N₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C16H16N2O4/c1-10(19)17-12-3-8-16(22)15(9-12)18(11(2)20)13-4-6-14(21)7-5-13/h3-9,21-22H,1-2H3,(H,17,19)
• InChI key: InChIKey=NQLVUMFRDUPEJZ-UHFFFAOYSA-N
• SMILES: CC(=O)Nc1ccc(O)c(N(C(C)=O)c2ccc(O)cc2)c1