(-)-alpha-Acetylmethadol Hydrochloride

CAS: 43033-72-3

Ref. TR-A186325

Product Information

• Name: (-)-alpha-Acetylmethadol Hydrochloride
• Synonyms: Benzeneethanol, ß-[(2S)-2-(dimethylamino)propyl]-a-ethyl-ß-phenyl-, 1-acetate, hydrochloride (1:1), (aS)-, Benzeneethanol, ß-[(2S)-2-(dimethylamino)propyl]-a-ethyl-ß-phenyl-, acetate (ester), hydrochloride, (aS)- (9CI), Benzeneethanol, ß-[2-(dimethylamino)propyl]-a-ethyl-ß-phenyl-, acetate (ester), hydrochloride, [S-(R*,R*)]-, LAAM hydrochloride, LAAM-HCl, Levacetyl methadol hydrochloride, Levomethadyl acetate hydrochloride, MK 790, Orlaam, l-Acetylmethadol hydrochloride, l-a-Acetylmethadol hydrochloride, a-l-Acetylmethadol hydrochloride, Levacetylmethadol Hydrochloride, (-)-a-Acetylmethadol Hydrochloride, (-)-(3S,6S)-6-(Dimethylamino)-4,4-diphenyl-3-heptanol acetate (ester), hydrochloride, (3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate hydrochloride (1:1), 3-Heptanol, 6-(dimethylamino)-4,4-diphenyl-, acetate (ester), hydrochloride, (3S,6S)-(-)-, 5-(acetyloxy)-N,N-dimethyl-4,4-diphenylheptan-2-aminium chloride, Benzeneethanol, beta-(2-(dimethylamino)propyl)-alpha-ethyl-beta-phenyl-, acetate (ester), hydrochloride, (S-(R*,R*))-, Benzeneethanol, β-[(2S)-2-(dimethylamino)propyl]-α-ethyl-β-phenyl-, 1-acetate, hydrochloride (1:1), (αS)-, Benzeneethanol, β-[(2S)-2-(dimethylamino)propyl]-α-ethyl-β-phenyl-, acetate (ester), hydrochloride, (αS)-, Benzeneethanol, β-[2-(dimethylamino)propyl]-α-ethyl-β-phenyl-, acetate (ester), hydrochloride, [S-(R*,R*)]-, Ccris 3321, Levomethadyl acetate HCl, Levomethadyl acetate hydrochloride [USAN], Mk 790, alpha-l-Acetylmethadol hydrochloride, l-alpha-Acetylmethadol hydrochloride, l-α-Acetylmethadol hydrochloride, α-l-Acetylmethadol hydrochloride
• CAS: 43033-72-3

Description

Applications (-)-α-Acetylmethadol Hydrochloride is a metabolite of methadone which is a potent non-competitive antagonist of α3β4 nicotinic receptor (nAChRs); Produce potent, naloxone-reversible tailflick analgesia.
References Xiao, Y., et al.: J. Pharmacol. Exp. Ther., 299, 366-371 (2001); Umans, J. G., et al.: Res. Commun. Substance, 2, 291-302 (1981)

• Brand: TRC

Chemical properties

• Molecular weight: 389.96
• Formula: C₂₃H₃₁NO₂•HCl
• Color/Form: Neat
• InChI: 1H/t18-,22-, /h7-16,18,22H,6,17H2,1-5H3, InChI=1S/C23H31NO2.ClH/c1-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21, /m0./s1
• InChI key: InChIKey=UXBPQRGCVJOTNT-COBSGTNCSA-N
• SMILES: CC[C@H](OC(C)=O)C(C[C@H](C)N(C)C)(c1ccccc1)c1ccccc1.Cl