1-(5-O-Acetyl-β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one

CAS: 1174733-90-4

Ref. TR-A188035

Product Information

• Name: 1-(5-O-Acetyl-β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one
• Synonyms: 1,3,5-Triazin-2(1H)-one, 1-(5-O-acetyl-ß-D-ribofuranosyl)-4-amino-, 1-(5-O-Acetyl-ß-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one

Description

Stability Moisture Sensitive
Applications 1-(5-O-Acetyl-β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one is an impurity of 5-Azacytidine (A796000), a potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase.
References Kusaba, H., et al.: Eur. J. Biochem., 262, 924 (1999), Broday, L., et al.: Mol. Cell Biol., 19, 3198 (1999), Qian, X., et al.: Am. J. Pathol., 153, 1475 (1999), Canova, C., et al.: Mech. Ageing Dev., 101, 153 (1998)

• Brand: TRC

Chemical properties

• Molecular weight: 286.24
• Formula: C₁₀H₁₄N₄O₆
• Color/Form: White To Off-White
• InChI: InChI=1S/C10H14N4O6/c1-4(15)19-2-5-6(16)7(17)8(20-5)14-3-12-9(11)13-10(14)18/h3,5-8,16-17H,2H2,1H3,(H2,11,13,18)/t5-,6-,7-,8-/m1/s1
• InChI key: InChIKey=KWSJMBAVTSNOTR-WCTZXXKLSA-N
• SMILES: CC(=O)OC[C@H]1O[C@@H](n2cnc(N)nc2=O)[C@H](O)[C@@H]1O