1-[(S)-3-(Acetylthio)isobutyryl]-L-proline Hydrate

CAS: 64838-55-7

Ref. TR-A188730

Product Information

• Name: 1-[(S)-3-(Acetylthio)isobutyryl]-L-proline Hydrate
• Synonyms: DU 1163, S-Acetylcaptopril Hydrate, (S)-1-[3-(Acetylthio)-2-methyl-1-oxopropyl]-L-proline Hydrate, (S,S)-1-(D-3-Acetylthio-2-methylpropanoyl)-L-proline Hydrate, (2S)-1-[(2S)-3-(acetylsulfanyl)-2-methylpropanoyl]pyrrolidine-2-carboxylate, (S,S)-1-(<span class="text-smallcaps">D</smallcap>-3-Acetylthio-2-methylpropanoyl)-<smallcap>L</span>-proline, 1-[(2S)-3-(Acetylsulfanyl)-2-methylpropanoyl]-L-proline, 1-[(2S)-3-(Acetylthio)-2-methyl-1-oxopropyl]-<span class="text-smallcaps">L</span>-proline, 1-[(2S)-3-(Acetylthio)-2-methyl-1-oxopropyl]-L-proline, 1-[3-(Acetylsulfanyl)-2-Methylpropanoyl]Proline, 1-[3-(acetylsulfanyl)-2-methylpropanoyl]-L-proline, <span class="text-smallcaps">L</span>-Proline, 1-[(2S)-3-(acetylthio)-2-methyl-1-oxopropyl]-, <span class="text-smallcaps">L</span>-Proline, 1-[3-(acetylthio)-2-methyl-1-oxopropyl]-, (S)-, Du 1163, L-proline, 1-[(2S)-3-(acetylthio)-2-methyl-1-oxopropyl]-, S-Acetylcaptopril
• CAS: 64838-55-7

Description

Applications 1-[(S)-3-(Acetylthio)isobutyryl]-L-proline Hydrate is used in the preparation of captopril derivatives, used as angiotensin converting enzymes.
References Li, H. et al.: Res. Chem. Intermed., 2, 621 (2013);

• Brand: TRC

Chemical properties

• Molecular weight: 259.32
• Formula: C₁₁H₁₇NO₄S
• Color/Form: Neat
• InChI: InChI=1S/C11H17NO4S/c1-7(6-17-8(2)13)10(14)12-5-3-4-9(12)11(15)16/h7,9H,3-6H2,1-2H3,(H,15,16)/t7-,9+/m1/s1
• InChI key: InChIKey=ZNQRGUYIKSRYCI-APPZFPTMSA-N
• SMILES: CC(=O)SC[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O