Estimated delivery in United States, on Friday 31 May 2024
Product Information
Name:
AdipoRon
Synonyms:
- 2-(4-Benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide
- 2-(4-Benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide
CAS:
Description:
Applications AdipoRon is an AdipoR agonist and activates AMPK and PPAR-α pathways in the muscle and liver. AdipoRon ameliorated diabetes of genetically obese rodent model db/db mice, and prolonged the shortened lifespan of db/db mice on a high-fat diet. AdipoRon is a promising therapeutic approach for the treatment of obesity-related diseases such as type 2 diabetes.
References Okada-Iwabu, M., et. al.: Nature, 503, 493 (2013)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
428.52
Formula:
C27H28N2O3
Color/Form:
Neat
InChI:
InChI=1S/C27H28N2O3/c30-26(28-24-15-17-29(18-16-24)19-21-7-3-1-4-8-21)20-32-25-13-11-23(12-14-25)27(31)22-9-5-2-6-10-22/h1-14,24H,15-20H2,(H,28,30)
InChI key:
InChIKey=SHHUPGSHGSNPDB-UHFFFAOYSA-N
SMILES:
O=C(COc1ccc(C(=O)c2ccccc2)cc1)NC1CCN(Cc2ccccc2)CC1
MDL:
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HS code:
Technical inquiry about: TR-A291670 AdipoRon
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