ACTH (1-24, Human) Acetic Acid Salt

CAS: 60189-34-6

Ref. TR-A305290

Product Information

• Name: ACTH (1-24, Human) Acetic Acid Salt
• Synonyms: alpha1-24-Adrenocorticotropic Hormone, alpha1-24-Corticotropin, (1-24)alpha-ACTH, 1-24 ACTH (human), 1-24 corticotropin (human), ACTH1-24, ACTHalpha1-24, Actholain, Adrenocorticotropin(1-24), Ba 30920, Ba 36716, Corticotropin-(1-24), Cortrophin S, Cortrosinta, Cortrosyn, Cosyntropin, Human ACTH (1-24), L-Seryl-L-tyrosyl-L-seryl-L-methionyl-L-glutamyl-L-alpha-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-proline, Nuvacthen Depot, PN: WO9952928, EQID: 9 claimed protein, Porcine ACTH (1-24), Synacthen, Synacthene, Synacthene-retard, Synecthen, Tetracosactid, Tetracosactide, Tetracosactrin, Tetracosapeptide, alpha1-24-ACTH, beta-Corticotrophin-(1-24)-tetracosapeptide, beta1-24-ACTH, beta1-24-Corticotropin, beta1-24-Tetracosactide, Tetracosactide acetate

Description

Applications α1-24-Adrenocorticotropic Hormone Acetic Acid Salt is used in the treatment of West syndrome (WS).
References Munakata, M., et. al.: Tohoku J. Exp. Med., 232, 273 (2014);

• Brand: TRC

Chemical properties

• Molecular weight: 2933.44 + x (60.05)
• Formula: C₁₃₆H₂₁₀N₄₀O₃₁S•x(CH₄O₂)
• Color/Form: White to Off-White Solid
• InChI: InChI=1S/C97H161N31O19.C32H46N8O11S.C2H4O2/c1-55(2)77(124-86(138)72-33-21-47-126(72)91(143)68(29-13-17-43-101)116-76(131)53-113-80(132)70(51-59-52-112-62-25-9-8-24-61(59)62)121-81(133)63(108-7)30-18-44-109-95(102)103)88(140)114-54-75(130)115-64(26-10-14-40-98)82(134)117-65(27-11-15-41-99)83(135)118-67(31-19-45-110-96(104)105)84(136)120-69(32-20-46-111-97(106)107)92(144)127-48-22-34-73(127)87(139)125-79(57(5)6)89(141)119-66(28-12-16-42-100)85(137)123-78(56(3)4)90(142)122-71(50-58-36-38-60(129)39-37-58)93(145)128-49-23-35-74(128)94(146)147;1-33-24(12-19-13-34-17-35-19)30(49)37-22(7-8-27(45)46)28(47)38-23(9-10-52-2)29(48)40-26(16-43)32(51)39-25(31(50)36-20(14-41)15-42)11-18-3-5-21(44)6-4-18;1-2(3)4/h8-9,24-25,36-39,52,55-57,63-74,77-79,108,112,129H,10-23,26-35,40-51,53-54,98-101H2,1-7H3,(H,113,132)(H,114,140)(H,115,130)(H,116,131)(H,117,134)(H,118,135)(H,119,141)(H,120,136)(H,121,133)(H,122,142)(H,123,137)(H,124,138)(H,125,139)(H,146,147)(H4,102,103,109)(H4,104,105,110)(H4,106,107,111);3-6,13-14,17,20,22-26,33,42-44H,7-12,15-16H2,1-2H3,(H,34,35)(H,36,50)(H,37,49)(H,38,47)(H,39,51)(H,40,48)(H,45,46);1H3,(H,3,4)/t63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,77-,78-,79-;20-,22+,23+,24+,25+,26+;/m01./s1
• InChI key: InChIKey=HEQZVTSLOFLUHI-AAFCTPIJSA-N
• SMILES: CC(=O)O.CN[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)O)C(C)C)C(C)C)C(C)C.CN[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C=O)CO