Product Information
Name:
Akt Inhibitor XI
Synonyms:
- (SP-4-3)-Dichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamide-κN2,κS]-copper
- FPA-124
Description:
Applications Akt inhibitor XI inhibits Akt in various cancer cells. Protein kinase B (PKB or Akt) is a serene/threonine kinase, which is involved in a wide variety of cellular processes including metabolism, apoptosis and cell proliferation. Furthermore, Akt inhibitor XI was employed in a biological study that aimed to develop a novel coiled-coil three-hybrid system that can identify potential allosteric inhibitors.
References Dan, S., et al.: Cancer Res. 70, 4982 (2010); Jester, B. W., et al.: J. Am. Chem. Soc. 132, 11727 (2010); Jester, B. W., et al.: J. Med. Chem. 55, 1526 (2012); Fedichev, P. O. and Vinnik, A. A. PCT Int. Appl. WO 2013147649 A2 20131003 (2013)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
381.73
Formula:
C11H9Cl2CuN3O2S
Color/Form:
Green Solid
SMILES:
Cl.N=C([S-])N/N=C\c1coc2ccccc2c1=O.[Cl-].[Cu+2]
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
