Product Information
Name:
Aloisine RP106
Synonyms:
- RP106, 7-n-Butyl-6-(4-methoxyphenyl)-[5H]pyrrolo[2,3-b]pyrazine
- 5H-pyrrolo[2,3-b]pyrazine, 7-butyl-6-(4-methoxyphenyl)-
Description:
Applications A cell-permeable pyrrolo-pyrazine compound that acts as a potent, selective, reversible, and ATP-competitive inhibitor of Cdk1/cyclin B, Cdk5/p35, and GSK-3 ( IC50 =700nM 1.5 uM, and 920 nM, respectively).
References Mattey, Y., et al.: J. Med. Chem., 46, 222 (2003)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
281.35
Formula:
C17H19N3O
Color/Form:
Off-White to Pale Yellow Solid
InChI:
InChI=1S/C17H19N3O/c1-3-4-5-14-15(12-6-8-13(21-2)9-7-12)20-17-16(14)18-10-11-19-17/h6-11H,3-5H2,1-2H3,(H,19,20)
InChI key:
InChIKey=WVMANZPBOBRWCB-UHFFFAOYSA-N
SMILES:
CCCCc1c(-c2ccc(OC)cc2)[nH]c2nccnc12
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