Alphadolone

CAS: 14107-37-0

Ref. TR-A575510

Product Information

• Name: Alphadolone
• Synonyms: Pregnane-11,20-dione, 3,21-dihydroxy-, (3a,5a)-, 5a-Pregnane-11,20-dione, 3a,21-dihydroxy- (8CI), (3a,5a)-3,21-Dihydroxypregnane-11,20-dione, 3a,21-Dihydroxy-5a-pregnane-11,20-dione, 5a-Pregnane-3a,21-diol-11,20-dione, Alfadolone, (3Α,5Α)-3,21-Dihydroxypregnane-11,20-Dione, 3-alpha,21-Dihydroxy-5-alpha-pregnane-11,20-dione, 3alpha,21-Dihydroxy-5alpha-pregnane-11,20-dione, 3α,21-Dihydroxy-5α-pregnane-11,20-dione, 5-alpha-Pregnane-11,20-dione, 3-alpha,21-dihydroxy-, 5α-Pregnane-11,20-dione, 3α,21-dihydroxy-, 5α-Pregnane-3α,21-diol-11,20-dione, Alfadolona, Alfadolona [INN-Spanish], Alfadolone [INN:DCF], Alfadolonum, Alfadolonum [INN-Latin], Gr 2/1574, Pregnane-11,20-dione, 3,21-dihydroxy-, (3α,5α)-, Unii-Oe1C96974E
• CAS: 14107-37-0

Description

Applications Alphadolone or Alfadolone (INN) is a neuroactive steroid with hypnotic effects. Alphadolone is one of the components of Althesin.
References Harrison, N., et al.: J. Pharmacol. Exp. Ther., 241, 346 (1987), Serrao, J., et al.: Anesthesiology, 70, 780 (1989), Mistry, D., et al.: Exp. Physiol., 75, 199 (1900),

• Brand: TRC

Chemical properties

• Molecular weight: 348.48
• Formula: C₂₁H₃₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C21H32O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h12-16,19,22-23H,3-11H2,1-2H3/t12-,13+,14-,15-,16+,19+,20-,21-/m0/s1
• InChI key: InChIKey=XWYBFXIUISNTQG-VKMGZQQJSA-N
• SMILES: C[C@]12CC(=O)[C@H]3[C@@H](CC[C@H]4C[C@H](O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)CO