AMI-193

CAS: 510-74-7

Ref. TR-A576605

Product Information

• Name: AMI-193
• Synonyms: 8-[3-(4-Fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, Fluroxyspiramine, Spiramide, 1,3,8-Triazaspiro(4.5)decan-4-one, 8-(3-(4-fluorophenoxy)propyl)-1-phenyl-, 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[3-(p-fluorophenoxy)propyl]-1-phenyl-, 8-(3-(4-Fluorophenoxy)propyl)-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one, 8-[3-(4-Fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one, Ami 193, Espiramida, Espiramida [INN-Spanish], R 5808, Spiramide (drug)?, Spiramide (pharmaceutical), Spiramide [INN], Spiramidum, Spiramidum [INN-Latin], Unii-471Lf4O004
• CAS: 510-74-7

Description

Applications AMI-193 is a selective 5-HT2A and D2DR receptor antagonist. Endoplasmic reticulum (ER) stress inducer; Also, it is derived from 4-Fluorophenol (F595325), which is a fluorinated phenolic compound with various applications as an starting reagent for the synthesis of pharmaceutical goods.
References Luparini, M. R., et al.: Prog. Neuropsychopharmacol. Biol. Psychiatry, 28, 1117-1127 (2004); Bi, K., et al.: Anal. Bioanal. Chem., 407, 5343-5351 (2015); Fujieda, N., et al.: J. Biol. Inorg. Chem., 18, 19 (2013);

• Brand: TRC

Chemical properties

• Molecular weight: 383.46
• Formula: C₂₂H₂₆FN₃O₂
• Color/Form: Off-White to Pale Yellow Solid
• InChI: InChI=1S/C22H26FN3O2/c23-18-7-9-20(10-8-18)28-16-4-13-25-14-11-22(12-15-25)21(27)24-17-26(22)19-5-2-1-3-6-19/h1-3,5-10H,4,11-17H2,(H,24,27)
• InChI key: InChIKey=FJUKDAZEABGEIH-UHFFFAOYSA-N
• SMILES: O=C1NCN(c2ccccc2)C12CCN(CCCOc1ccc(F)cc1)CC2