Amifostine Thiol Dihydrochloride (90%)

CAS: 14653-77-1

Ref. TR-A576820

Product Information

• Name: Amifostine Thiol Dihydrochloride (90%)
• Synonyms: 2-(3-aminopropylamino)ethanethiol;dihydrochloride, Ethanethiol, 2-[(3-aminopropyl)amino]-, dihydrochloride, Ethanethiol, 2-[(3-aminopropyl)amino]-, hydrochloride (1:2), Wr 1065, ethanethiol, 2-[(3-aminopropyl)amino]-, 2-((3-Aminopropyl)Amino)Ethanethiol Dihydrochloride, 2-((3-Aminopropyl)amino)ethyl hydrosulfide, WR-1065 hydrochloride

Description

Stability Hygroscopic
Applications Amifostine Thiol is a metabolite of Amifostine (A576810) which provides normal cells with selective protection against the toxic effects of cancer chemotherapy and radiation treatment.
References Satge, J., et al.: Eur. J. Med. Chem., 24, 48 (1989); Geary, R.S., et al.: Biopharm. Drug Dispos., 12, 261 (1991); Brown, D.Q., et al. Pharmacol. Ther., 39, 159 (1988); Capizzi, R.L., et al.: Cancer, 72, 3495 (1993); Treskes, M., et al.: Cancer Chemother. Pharmacol., 33, 93 (1993)

• Brand: TRC

Chemical properties

• Molecular weight: 207.16
• Formula: C₅H₁₄N₂SClH
• Purity: 90%
• Color/Form: Off-White
• InChI: InChI=1S/C5H14N2S.2ClH/c6-2-1-3-7-4-5-8, 2*1H, /h7-8H,1-6H2,