5-Amino-N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide

CAS: 60166-98-5

Ref. TR-A601550

Product Information

• Name: 5-Amino-N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide
• Synonyms: 5-Amino-N1,N3-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide, 5-Amino-N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodobenzene-1,3-dicarboxamide, Iopamidol impurity A, N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethy]-5-amino-2,4,6-tri-iodoisophthalamide, Iopamidol Related Compound A, Iopamidol Impurity A

Description

Impurity Iopamidol EP Impurity A
Applications 5-Amino-N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide (Iopamidol EP Impurity A) is an impurity in the synthesis of Iopamidol (I735600), a nonionic radiocontrast medium. Diagnostic aid (radiopaque medium).
References Drayer, B., et al.: Am. J. Neuroradiol., 3, 59 (1982), Molyneux, A.J., et al.: Br. J. Radiol., 55, 117 (1982), Sovak, M., et al.: Radiology, 142, 115 (1982), Felder, E., et al.: Anal. Profiles Drug Subs., 17, 115 (1988),

• Brand: TRC

Chemical properties

• Molecular weight: 705.02
• Formula: C₁₄H₁₈I₃N₃O₆
• Color/Form: White to Off-White Solid
• InChI: InChI=1S/C14H18I3N3O6/c15-9-7(13(25)19-5(1-21)2-22)10(16)12(18)11(17)8(9)14(26)20-6(3-23)4-24/h5-6,21-24H,1-4,18H2,(H,19,25)(H,20,26)
• InChI key: InChIKey=FVLWRKHQMFPOQE-UHFFFAOYSA-N
• SMILES: Nc1c(I)c(C(=O)NC(CO)CO)c(I)c(C(=O)NC(CO)CO)c1I