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3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS: 1224844-38-5
Ref. TR-A602050
| 5mg | 94.00 € | ||
| 50mg | 400.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Product Information
Name:
3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Controlled Product
Synonyms:
- INK 128
- MLN 0128
- Sapanisertib
- 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(2-amino-5-benzoxazolyl)-1-(1-methylethyl)-
Description:
Stability Hygroscopic
Applications 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a potent and selective TORC1/2 inhibitor with broad oral antitumor activity. TORC1/2 inhibitors are mechanistically distinct from rapamycinand offer a compelling approach to the treatment of cancer by targeting translational control, cell metabolism, growth andangiogenesis.
References Katayoun, J., et al.: Molec. Cancer. Therap., 8, 1158 (2009);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
309.33
Formula:
C15H15N7O
Color/Form:
Neat
InChI:
InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
InChI key:
InChIKey=GYLDXIAOMVERTK-UHFFFAOYSA-N
SMILES:
CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc21
MDL:
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