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3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
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3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

CAS: 1224844-38-5

Ref. TR-A602050

5mg
94.00 €
50mg
400.00 €
Estimated delivery in United States, on Friday 21 Jun 2024

Product Information

Name:
3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Controlled Product
Synonyms:
  • INK 128
  • MLN 0128
  • Sapanisertib
Description:

Stability Hygroscopic
Applications 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a potent and selective TORC1/2 inhibitor with broad oral antitumor activity. TORC1/2 inhibitors are mechanistically distinct from rapamycinand offer a compelling approach to the treatment of cancer by targeting translational control, cell metabolism, growth andangiogenesis.
References Katayoun, J., et al.: Molec. Cancer. Therap., 8, 1158 (2009);

Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
309.33
Formula:
C15H15N7O
Color/Form:
White to Off-White Solid
InChI:
InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
InChI key:
InChIKey=GYLDXIAOMVERTK-UHFFFAOYSA-N
SMILES:
CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc21
MDL:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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