Product Information
- (2S)-2-Amino-4-bromobutyric Acid Hydrobromide
- (S)-2-Amino-4-bromobutyric Acid Hydrobromide
- L-2-Amino-4-bromobutyric Acid Hydrobromide
- (S)-(+)-2-Amino-4-bromobutyric acid hydrobromide
- (2S)-2-amino-4-bromobutanoic acid
- (2S)-2-amino-4-bromobutanoic acid hydrobromide
- L(+)-2-Amino-4-Bromobutyric Acid Hydrobromide
Stability Unstable in Solution, Moisture Sensitive, Hygroscopic
Applications (S)-(+)-2-Amino-4-bromobutyric Acid Hydrobromide is a building block used in stereoselective preparation of phosphinic acid phosphapeptide analogs of glutamyl-γ-glutamate as potent inhibitors of folylpolyglutamate synthetase. Also used in the synthesis of isoindoline carbamate and acylsulfonamide containing macrocyclic peptidomimetics as inhibitors of HCV NS3/4A protease.
References Bartley, D., et al.: J. Org. Chem., 70, 6757 (2005); Jiang, Y., et al.: J. Med. Chem., 57, 1753 (2014);
Chemical properties
Technical inquiry about: TR-A602465 (S)-(+)-2-Amino-4-bromobutyric Acid Hydrobromide (~90%)
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