2-Amino-5,6-dichloro-3(4H)-quinazoline Acetic Acid Hydrobromide (Anagrelide Impurity B)

CAS: 1194434-39-3

Ref. TR-A604745

Product Information

• Name: 2-Amino-5,6-dichloro-3(4H)-quinazoline Acetic Acid Hydrobromide (Anagrelide Impurity B)
• Synonyms: USP Anagrelide Related Impurity B Hydrobromide

Description

Impurity Anagrelide USP Related Impurity B Hydrobromide;
Applications Anagrelide impurity B. Quinazolines derivatives are attractive targets because they form an important component of pharmacologically active compounds and are associated with a wide spectrum of biological activities ranging from anticonvulsant and antibacterial to antidiabetic.
References Molamas, M.S., et al.: J. Med. Chem., 34, 1492 (1991), Brogden, R.N., et al.: Drugs, 47, 809 (1994), Brase, S., et al.: Bioorg. Med. Chem. Lett., 10, 2415 (2002),

• Brand: TRC

Chemical properties

• Molecular weight: 355.02
• Formula: C₁₀H₁₀BrCl₂N₃O₂
• Color/Form: White
• InChI: InChI=1S/C10H9Cl2N3O2.BrH/c11-6-1-2-7-5(9(6)12)3-15(4-8(16)17)10(13)14-7;/h1-2H,3-4H2,(H2,13,14)(H,16,17);1H
• InChI key: InChIKey=YVUNMMZTHKHYMZ-UHFFFAOYSA-N
• SMILES: Br.NC1=Nc2ccc(Cl)c(Cl)c2CN1CC(=O)O