2-Amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile

CAS: 69205-79-4

Ref. TR-A605080

Product Information

• Name: 2-Amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
• Synonyms: 2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, 7-Cyano-7-deazaguanine, PreQ0, 2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, 2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, 3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, 2-amino-4,7-dihydro-4-oxo-

Description

Applications 2-Amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile is a reagent used for structure-based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1.
References Khalaf, A.I., et al.: J. Med. Chem., 57, 6479 (2014); Barrett, M., et al.: Br. J. Pharmacol., 152, 1155 (2007)

• Brand: TRC

Chemical properties

• Molecular weight: 175.148
• Formula: C₇H₅N₅O
• Color/Form: Dark Red Solid
• InChI: InChI=1S/C7H5N5O/c8-1-3-2-10-5-4(3)6(13)12-7(9)11-5/h2H,(H4,9,10,11,12,13)
• InChI key: InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
• SMILES: N#Cc1c[nH]c2nc(N)[nH]c(=O)c12