2-Aminoethyl Methanethiosulfonate Hydrobromide

CAS: 16599-33-0

Ref. TR-A609100

Product Information

• Name: 2-Aminoethyl Methanethiosulfonate Hydrobromide
• Synonyms: 2-methylsulfonylsulfanylethanamine;hydrobromide, methanesulfonothioic acid, S-(2-aminoethyl) ester

Description

Stability Hygroscopic
Applications 2-Aminoethyl Methanethiosulfonate Hydrobromide reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease. Useful for mapping the pore-lining regions of the ryanodine receptor.
References Yang, N. et al.: Neuron, 16, 113 (1996), Kuner, T. et al.: Neuron, 17, 343 (1996), Holmgren, M. et al: Neuropharmacology, 35, 797 (1996) Chahine, M. et al.: Biochemical & Biophysical Res. Commun., 233, 606 (1997), Ehrlich, B.E., et al.: J. Gen. Physiol., 109, 255 (1997), Rassendren, F., et al.: The EMBO Journal, 16, 3446 (1997), Egan, T.M., et al.: The Journal of Neuroscience, 18(7), 2350 (1998), Lin, C.-W. and Tsung-Yu, C.: J. Gen. Physiol., 116, 535 (2000)

• Brand: TRC

Chemical properties

• Molecular weight: 236.15
• Formula: C₃H₉NO₂S₂·BrH
• Color/Form: Neat
• InChI: InChI=1S/C3H9NO2S2.BrH/c1-8(5,6)7-3-2-4;/h2-4H2,1H3;1H
• InChI key: InChIKey=DMVGEUBCWCKGMY-UHFFFAOYSA-N
• SMILES: Br.CS(=O)(=O)SCCN