(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one
CAS: 115992-91-1
Ref. TR-A609220
| 10mg | 253.00 € | ||
| 100mg | 1,698.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Product Information
Name:
(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one
Controlled Product
Synonyms:
- N,N-Didesmethyl-O-desmethyl-O'-desacetyl Diltiazem
- (2S-cis)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one
Description:
Applications (2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one is an impurity of diltiazem (D460620). Diltiazem Hydrochloride is a calcium channel blocker with vasodilating activity. Anti-anginal; anti-hypertensive; anti-arrhythmic (class IV).
References Sato, et al.: Arzneim.-Forsch., 21, 1338 (1971), Smirnov, S.R.: Eur. J. Pharmacol., 360, 81 (1998), Hansson, L., et al.: Lancet, 356, 359 (2000),
Notice:
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Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
330.4
Formula:
C17H18N2O3S
Color/Form:
Neat
InChI:
InChI=1S/C17H18N2O3S/c18-9-10-19-13-3-1-2-4-14(13)23-16(15(21)17(19)22)11-5-7-12(20)8-6-11/h1-8,15-16,20-21H,9-10,18H2/t15-,16+/m1/s1
InChI key:
InChIKey=NIQVIAXYLUEION-CVEARBPZSA-N
SMILES:
NCCN1C(=O)[C@H](O)[C@H](c2ccc(O)cc2)Sc2ccccc21
MDL:
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Technical inquiry about: TR-A609220 (2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one
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