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4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide

CAS:

Ref. TR-A609725

1g
508.00€
250mg
190.00€
2500mg
952.00€
4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
TRC

Product Information

Name:4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
Controlled Product
Synonyms:
  • 2-Pyridinecarboxamide
  • 4-(4-amino-3-fluorophenoxy)-N-methyl-
  • 4-(4-Amino-3-fluorophenoxy)-N-methyl-2-pyridinecarboxamide
  • 4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic acid methylamide
Brand:TRC
Description:Applications 4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide is a compound used as a reagent to synthesize Regorafenib (R143000), a multikinase inhibitor that is used to treat patients with advanced colorectal cancer.References Mross, K., et al.: Clin. Cancer Res., 18, 2658 (2012); Stiehl, J., et al. Process for Preparation of Regorafenib. PCT Int. Appl. 2011128261. Oct 20, 2011; Van Cutsem, E., et al.: J. Clin. Oncol., 30, 3502 (2012)
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:261.25
Formula:C13H12FN3O2
Color/Form:Dark Orange To Red Brown
InChI:InChI=1S/C13H12FN3O2/c1-16-13(18)12-7-9(4-5-17-12)19-8-2-3-11(15)10(14)6-8/h2-7H,15H2,1H3,(H,16,18)
InChI key:InChIKey=ZQHJPIPGBODVTG-UHFFFAOYSA-N
SMILES:CNC(=O)c1cc(Oc2ccc(N)c(F)c2)ccn1

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