4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
CAS: 757251-39-1
Ref. TR-A609725
| 1g | 511.00 € | ||
| 250mg | 189.00 € | ||
| 2500mg | 981.00 € |
Estimated delivery in United States, on Wednesday 29 May 2024
Product Information
Name:
4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
Synonyms:
- 4-(4-Amino-3-fluorophenoxy)-N-methyl-2-pyridinecarboxamide
- 2-Pyridinecarboxamide, 4-(4-amino-3-fluorophenoxy)-N-methyl-
- 4-(4-Amino-3-Fluorophenoxy)-N-Methylpicolinamide
- 4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic acid methylamide
CAS:
Description:
Applications 4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide is a compound used as a reagent to synthesize Regorafenib (R143000), a multikinase inhibitor that is used to treat patients with advanced colorectal cancer.
References Mross, K., et al.: Clin. Cancer Res., 18, 2658 (2012); Stiehl, J., et al. Process for Preparation of Regorafenib. PCT Int. Appl. 2011128261. Oct 20, 2011; Van Cutsem, E., et al.: J. Clin. Oncol., 30, 3502 (2012)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
261.25
Formula:
C13H12FN3O2
Color/Form:
Dark Orange To Red Brown
InChI:
InChI=1S/C13H12FN3O2/c1-16-13(18)12-7-9(4-5-17-12)19-8-2-3-11(15)10(14)6-8/h2-7H,15H2,1H3,(H,16,18)
InChI key:
InChIKey=ZQHJPIPGBODVTG-UHFFFAOYSA-N
SMILES:
CNC(=O)c1cc(Oc2ccc(N)c(F)c2)ccn1
MDL:
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HS code:
Technical inquiry about: TR-A609725 4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
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