(S)-(-)-4-Amino-2-hydroxybutyric Acid

CAS: 40371-51-5

Ref. TR-A611245

Product Information

• Name: (S)-(-)-4-Amino-2-hydroxybutyric Acid
• Synonyms: Amikacin Sulfate Imp. I (EP), Amikacin Imp. I (EP), (2S)-4-Amino-2-hydroxybutanoic Acid, Butanoic acid, 4-amino-2-hydroxy-, (S)-, (2S)-4-Amino-2-hydroxybutanoic acid, (S)-4-Amino-2-hydroxybutanoic acid, 4-Amino-(2S)-hydroxybutyric acid, L-(-)-4-Amino-2-hydroxybutyric acid, L-(-)-gamma-Amino-alpha-hydroxybutyric acid, L-4-Amino-2-hydroxybutyric acid, L-gamma-Amino-alpha-hydroxybutyric acid, Amikacin Impurity I, Amikacin Sulfate Impurity I, Amikacin Impurity I, 2-Hydroxy-4-amino Butanoic Acid(HABA), 2-Hydroxy-4-amino Butanoic Acid, (S)-(-)-4-Amino-2-hydroxybutyric acid, )-4-Amino-2-hydroxybutyric acid, 4-Amino-2-Hydroxybutanoic Acid, (2S)-4-amino-2-hydroxybutanoic acid, (2R)-4-amino-2-hydroxybutanoic acid

Description

Stability Hygroscopic
Applications (S)-(-)-4-Amino-2-hydroxybutyric Acid is an analogue of γ-aminobutyric acid (GABA) with potential inhibitory activity on GABA binding and uptake by brain. Injection of (S)-(-)-4-Amino-2-hydroxybutyric Acid showed no significant changes in plasma growth hormone (GH) in healthy patients but increased plasma GH, prolactin, and cortisol levels in cerebrovascular patients.
References Honore, T. et al.: Eur. J. Med. Chem., 13, 429 (1978); Takahara, J. et al.: Horm. Metab. Res., 12, 31 (1980);

• Brand: TRC

Chemical properties

• Molecular weight: 119.12
• Formula: C₄H₉NO₃
• Color/Form: Neat
• InChI: InChI=1S/C4H9NO3/c5-2-1-3(6)4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1
• InChI key: InChIKey=IVUOMFWNDGNLBJ-VKHMYHEASA-N
• SMILES: NCC[C@H](O)C(=O)O