8-Amino-Inosine

CAS: 13389-16-7

Ref. TR-A611855

Product Information

• Name: 8-Amino-Inosine
• Synonyms: NSC 109320

Description

Applications 8-Amino-Inosine is an derivative of Inosine (I661000), a nucleoside that is found in tRNAs and is essential for the proper translation of genetic code in a wobble base pair. Inosine is also known to exert neuroprotective properties and has been used to treat stroke patients to restore neural function. 8-Amino-Inosine have been studied as a potential chemotherapeutic agent for the treatment of leukemia function by the cytodestruction of the neoplastic cells.
References Vandemeulebroucke A, et al. 2010. Biochemistry. 2010 Oct 19;49(41):8999-9010Nestor G, et al. 2010. J Agric Food Chem. 2010 Oct 27;58(20):10799-803 Lin TS, et al. 1985. J Med Chem. 1985 Oct;28(10):1481-5.

• Brand: TRC

Chemical properties

• Molecular weight: 283.24
• Formula: C₁₀H₁₃N₅O₅
• Color/Form: Neat
• InChI: InChI=1S/C10H13N5O5/c11-10-14-4-7(12-2-13-8(4)19)15(10)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H2,11,14)(H,12,13,19)
• InChI key: InChIKey=OBCXRIVPFSZZSN-UHFFFAOYSA-N
• SMILES: Nc1nc2c(=O)nc[nH]c2n1C1OC(CO)C(O)C1O