2-(Aminomethyl)pyrazine

CAS: 20010-99-5

Ref. TR-A617440

Product Information

• Name: 2-(Aminomethyl)pyrazine
• Synonyms: (Aminomethyl)-pyrazine, Pyrazinemethanamine, NSC 105567, Pyrazin-2-ylmethanamine, [(Pyrazin-2-yl)methyl]amine, 2-Aminomethylpyrazine, 1-(Pyrazin-2-Yl)Methanamine, 2-Pyrazinemethanamine, Pyrazin-2-Ylmethanamine
• CAS: 20010-99-5

Description

Applications 2-(Aminomethyl)pyrazine is a useful synthetic intermediate. It is used to synthesize pyrazolo[4,3-c]pyridinediones as orally bioavailable NADPH oxidase isoform 4 inhibitors for the treatment of idiopathic pulmonary fibrosis. It is also used to prepare pyrazolyl-indoles with the abilities to induce T-cell kinase inhibition.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Laleu, B., et al.: J. Med. Chem., 53, 7715 (2010); Velankar, A., et al.: Bioorg. Med. Chem., 18, 4547 (2010)

• Brand: TRC

Chemical properties

• Molecular weight: 109.129
• Formula: C₅H₇N₃
• Color/Form: Neat
• InChI: InChI=1S/C5H7N3/c6-3-5-4-7-1-2-8-5/h1-2,4H,3,6H2
• InChI key: InChIKey=QGZYDVAGYRLSKP-UHFFFAOYSA-N
• SMILES: O=C(CCCCCCNC(=O)c1cnc(N(c2ccccc2)c2ccccc2)nc1)NO