(3S)-3-(2-Amino-2-oxo-1,1-diphenylethyl)-1,1-bis[2-(2,3-dihydro-5-benzofuranyl)ethyl]pyrrolidinium Bromide

CAS: 1396968-57-2

Ref. TR-A619020

Product Information

• Name: (3S)-3-(2-Amino-2-oxo-1,1-diphenylethyl)-1,1-bis[2-(2,3-dihydro-5-benzofuranyl)ethyl]pyrrolidinium Bromide
• Synonyms: 2-[(3S)-1,1-bis[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-1-ium-3-yl]-2,2-diphenylacetamide;bromide

Description

Applications (3S)-3-(2-Amino-2-oxo-1,1-diphenylethyl)-1,1-bis[2-(2,3-dihydro-5-benzofuranyl)ethyl]pyrrolidinium Bromide is an impurity of Darifenacin (D193400, HBr); a medication used to treat urinary incontinence. It works by blocking the M3 muscarinic acetylcholine receptor.
References Beaumont, K.C., et al.: Xenobiotica, 28, 63 (1998); Chapple, C.R., et al.: Expert Opin. Invest. Drugs, 13, 1493 (2004); Haab, F., et al.: Eur. Urol., 45, 420 (2004); Pramanik, Ch., et al.: Org. Process Res. Dev., 16, 1591 (2012)

• Brand: TRC

Chemical properties

• Molecular weight: 653.648
• Formula: C₃₈H₄₁N₂O₃·Br
• Color/Form: Neat
• InChI: InChI=1S/C38H40N2O3.BrH/c39-37(41)38(32-7-3-1-4-8-32,33-9-5-2-6-10-33)34-17-22-40(27-34,20-15-28-11-13-35-30(25-28)18-23-42-35)21-16-29-12-14-36-31(26-29)19-24-43-36;/h1-14,25-26,34H,15-24,27H2,(H-,39,41);1H/t34-;/m1./s1
• SMILES: NC(=O)C(c1ccccc1)(c1ccccc1)[C@@H]1CC[N+](CCc2ccc3c(c2)CCO3)(CCc2ccc3c(c2)CCO3)C1.[Br-]