2-(Aminomethyl)-5-hydroxy-6-oxo-N-(2,4,6-trifluorobenzyl)-1,6-dihydropyrimidine-4-carboxamide
Ref. TR-A622010
| 5mg | Discontinued | ||
| 10mg | Discontinued | ||
| 2500µg | Discontinued |
Product Information
Name:
2-(Aminomethyl)-5-hydroxy-6-oxo-N-(2,4,6-trifluorobenzyl)-1,6-dihydropyrimidine-4-carboxamide
Description:
Applications 2-(Aminomethyl)-5-hydroxy-6-oxo-N-(2,4,6-trifluorobenzyl)-1,6-dihydropyrimidine-4-carboxamide is an intermediate used in the synthesis of N-((5-Hydroxy-6-oxo-4-((2,4,6-trifluorobenzyl)carbamoyl)-1,6-dihydropyrimidin-2-yl)methyl)-1,3,4-oxadiazole-2-carboxamide (H950690), which is a derivative of Raltegravir (R100305), a potent integrase (IN) inhibitor for WT and S217Q PFV IN.
References Hare, S., et al.: Proc. Natl. Acad. Sci. U. S. A., 107, 20057 (2010); Hicks, C., et al.: Clin. Infect. Dis., 48, 931 (2009); Moss, D., et al.: Antimicrob. Agents Chemother., 56, 3020 (2012); Hare, S., et al.: Mol. Pharmacol., 80, 565 (2011)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
328.247
Formula:
C13H11F3N4O3
Color/Form:
Off-white Solid
InChI:
InChI=1S/C13H11F3N4O3/c14-5-1-7(15)6(8(16)2-5)4-18-12(22)10-11(21)13(23)20-9(3-17)19-10/h1-2,21H,3-4,17H2,(H,18,22)(H,19,20,23)
InChI key:
InChIKey=YJBYCVZEQSBAIG-UHFFFAOYSA-N
SMILES:
NCc1nc(C(=O)NCc2c(F)cc(F)cc2F)c(O)c(=O)[nH]1
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