N-[4-[(4-Aminophenyl)sulfonyl]phenyl]formamide

CAS: 21501-24-6

Ref. TR-A626895

Product Information

• Name: N-[4-[(4-Aminophenyl)sulfonyl]phenyl]formamide
• Synonyms: N-[4-(4-aminophenyl)sulfonylphenyl]formamide

Description

Applications N-[4-[(4-Aminophenyl)sulfonyl]phenyl]formamide is a dihydropteroate synthetase inhibitor. Also, it is a derivative of the parent compound, Dapsone (D193250), which is an antibacterial used in the treatment of dermatitis herpetiformis.
References Ho, R. I., et al.: Antimicrob. Agents Chemother., 7, 758-763 (1975); Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950), Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009), Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 276.311
• Formula: C₁₃H₁₂N₂O₃S
• Color/Form: Neat
• InChI: InChI=1S/C13H12N2O3S/c14-10-1-5-12(6-2-10)19(17,18)13-7-3-11(4-8-13)15-9-16/h1-9H,14H2,(H,15,16)
• InChI key: InChIKey=OUBLSNZSHXQKRB-UHFFFAOYSA-N
• SMILES: Nc1ccc(S(=O)(=O)c2ccc(NC=O)cc2)cc1