1-[(3-Amino-4-quinolinyl)amino]-2-methyl-2-propanol
CAS: 129655-59-0
Ref. TR-A629168
100mg | 180.00 € | ||
250mg | 382.00 € | ||
500mg | 718.00 € |
Product Information
- 1-[(3-Aminoquinolin-4-yl)amino]-2-methylpropan-2-ol
- 3-Amino-4-(2-hydroxy-2-methylpropylamino)quinoline
Applications 1-[(3-Amino-4-quinolinyl)amino]-2-methyl-2-propanol is an intermediate in synthesizing Resiquimod-d5 (R144682), an isotope labelled Resiquimod (R144680) which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.
References Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008)
Chemical properties
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