(Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetic Acid

CAS: 75028-24-9

Ref. TR-A630545

Product Information

• Name: (Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetic Acid
• Synonyms: (Z)-1,2,4-5-amino-alpha-(ethoxyimino)-thiadiazole-3-acetic Acid, (alphaZ)-5-Amino-alpha-(ethoxyimino)-1,2,4-thiadiazole-3-acetic Acid, (Z)-5-Amino-alpha-(ethoxyimino)-1,2,4-thiadiazole-3-acetic acid, (αZ)-5-Amino-α-(ethoxyimino)-1,2,4-thiadiazole-3-acetic acid, 1,2,4-Thiadiazole-3-acetic acid, 5-amino-α-(ethoxyimino)-, (Z)-, 1,2,4-Thiadiazole-3-acetic acid, 5-amino-α-(ethoxyimino)-, (αZ)-, Atde, Ceftazidime Norlin Intermediates

Description

Applications (Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetic Acid is an important intermediate for the preparation of Ceftaroline which possesses antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and P. aeruginosa.
References Kishi, K., et al.: J. Antibiot., 52, 1152-1155 (1999)

• Brand: TRC

Chemical properties

• Molecular weight: 216.22
• Formula: C₆H₈N₄O₃S
• Color/Form: Pale Beige Solid
• InChI: InChI=1S/C6H8N4O3S/c1-2-13-9-3(5(11)12)4-8-6(7)14-10-4/h2H2,1H3,(H,11,12)(H2,7,8,10)/b9-3-
• InChI key: InChIKey=UFTDZEXQFNFPFR-OQFOIZHKSA-N
• SMILES: CCO/N=C(\C(=O)O)c1nc(=N)s[nH]1