Product Information
- 3,5-Dichloro-4-aminopyridine N-Oxide
- 3,5-Dichloro-4-pyridinamine 1-Oxide
- 4-Amino-3,5-dichloropyridine N-oxide
- 91872-02-5
Applications 4-Amino-3,5-dichloropyridine N-Oxide is the impurity of the drug Roflumilast (R639700), which is a selective phosphodiesterase 4(PDE4) inhibitor, antiasthmatic.
References Hatzelmann, A., et al.: J. Pharmacol. Exp. Ther., 297, 267 (2001); Schmidt, B.M.W., et al.: J. Allergy Clin. Immunol., 108, 530 (2001); Timmer, W., et al.: J. Clin. Pharmacol., 42, 297 (2002); Rabe, K.F., et al.: Lancet, 366, 563 (2005);
Chemical properties
Technical inquiry about: TR-A632005 4-Amino-3,5-dichloropyridine N-Oxide
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