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Product Information
Name:
(R)-Amlodipine-d4
Controlled Product
Synonyms:
- 3-O-ethyl 5-O-methyl (4S)-2-[(2-amino-1,1,2,2-tetradeuterioethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
CAS:
Description:
Applications A labelled (R)-enantiomer of Amlodipine (A633495). A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.
References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987); Haria, M., et al.: Drugs, 50, 560 (1995);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
412.90
Formula:
C20H21D4ClN2O5
Color/Form:
Neat
InChI:
InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3/t17-/m0/s1/i9D2,10D2
InChI key:
InChIKey=HTIQEAQVCYTUBX-BISFPMKOSA-N
SMILES:
[2H]C([2H])(N)C([2H])([2H])OCC1=C(C(=O)OCC)[C@H](c2ccccc2Cl)C(C(=O)OC)=C(C)N1
MDL:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-A633492 (R)-Amlodipine-d4
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