Anhydro Dihydro Artemisinin

CAS: 82596-30-3

Ref. TR-A637875

Product Information

• Name: Anhydro Dihydro Artemisinin
• Synonyms: (3R,5aS,6R,8aS,12R,12aR)-3,4,5,5a,6,7,8,8a-Octahydro-3,6,9-trimethyl--3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, (+)-9,10-Anhydrodehydroartemisinin, 9,10-Anhydro-10-deoxoartemisinin, 9,10-Anhydrodehydroartemisinin, Anhydrodihydroartemisinin, Anhydrodihydroartemisnin, 3, 2-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, 3,4,5,5a,6,7,8,8a-octahydro-3,6,9-trimethyl-, [3R-(3alpha,5abeta,6beta,8abeta,12beta,12aR*)]-, Artesunate Related Compound C

Description

Applications Anhydrodihydroartemisinin is a semisynthetic derivative of Artersiminin (A777500). Anhydrodihydroartemisinin is a decomposition product of Artesunate (A777800) and Dihydroartemisinin (D448360). Anhydrodihydroartemisinin showed antimalarial activity although much weaker than its parent compound.
References Haynes, R.K. et al.: ChemMedChem, 2, 1448 (2007); Lin, A.J. et al.: Am. J. Trop. Med. Hyg., 50, 777 (1994); Galal, A. et al.: J. Nat. Prod., 68, 1274 (2005);

• Brand: TRC

Chemical properties

• Molecular weight: 266.33
• Formula: C₁₅H₂₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C15H22O4/c1-9-4-5-11-10(2)8-16-13-15(11)12(9)6-7-14(3,17-13)18-19-15/h8-9,11-13H,4-7H2,1-3H3/t9-,11+,12+,13-,14-,15+/m1/s1
• InChI key: InChIKey=UKXCIQFCSITOCY-VLDCTWHGSA-N
• SMILES: CC1=CO[C@@H]2O[C@@]3(C)CC[C@H]4[C@H](C)CC[C@@H]1[C@]42OO3