5-Androsten-3β-ol-17-one Ethyleneketal-d8

CAS: 7745-40-6

Ref. TR-A637947

Product Information

• Name: 5-Androsten-3β-ol-17-one Ethyleneketal-d8
• Synonyms: 17,17-(Ethylenedioxy)androst-5-en-3ß-ol-d8, 3ß-Hydroxyandrost-5-en-17-one Cyclic Ethylene Acetal-d8

Description

Applications Androst-5-en-17-one-7β-d 3β-Hydroxy-cyclic Ethylene Acetal is an intermediate in the synthesis of Dehydroepiandrosterone-d5 which is the labeled analogue of Dehydro Epiandrosterone (D229585). Dehydro Epiandrosterone is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome.
References Yahara, M., et al.: J. Toxicol. Sci., 2, 161 (1977), Morales, A.J., et al.: J. Clin. Endocrinol. Metab., 78, 1360 (1994), Ebeling, P., et al.: Lancet, 343, 1479 (1994),

• Brand: TRC

Chemical properties

• Molecular weight: 340.53
• Formula: C₂₁H₂₄D₈O₃
• Color/Form: Neat
• InChI: InChI=1S/C21H32O3/c1-19-8-5-15(22)13-14(19)3-4-16-17(19)6-9-20(2)18(16)7-10-21(20)23-11-12-24-21/h3,15-18,22H,4-13H2,1-2H3/t15-,16+,17-,18-,19-,20-/m0/s1/i3D,5D2,10D2,13D2,15D
• InChI key: InChIKey=FUSUHKVFWTUUBE-UHFFFAOYSA-N
• SMILES: C=CC(C)=O