5α-Androst-8(14)-ene-3,17-dione

CAS: 17305-45-2

Ref. TR-A638125

Product Information

• Name: 5α-Androst-8(14)-ene-3,17-dione
• Synonyms: (5S,9R,10S,13S)-10,13-dimethyl-2,4,5,6,7,9,11,12,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione

Description

Applications 5α-Androst-8(14)-ene-3,17-dione is the impurity of Testosterone (T155000), which is the principal hormone of the testes, produced by the interstitial cells. Testosterone is the major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone that is required for normal male sexual differentiation.
References McFarland, K., et al.: Science, 245, 494 (1989); Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998); Themmen, A., et al.: Endocr. Rev. 21, 551 (2000); Kumar, R., et al.: Biol. Reprod., 65, 710 (2001);

• Brand: TRC

Chemical properties

• Molecular weight: 286.409
• Formula: C₁₉H₂₆O₂
• Color/Form: Neat
• InChI: InChI=1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,16H,3-11H2,1-2H3/t12-,16-,18-,19-/m0/s1
• InChI key: InChIKey=UPPWIMHSTQMTHM-DMBMUNPASA-N
• SMILES: C[C@]12CC[C@H]3C(=C1CCC2=O)CC[C@H]1CC(=O)CC[C@@]13C