Product Information
- 6-anilinoquinoline-5,8-dione
- 5,8-Dihydro-5,8-dioxo-6-(phenylamino)quinoline
- 5,8-Quinolinedione, 6-(phenylamino)-
- 6-(Phenylamino)-5,8-quinolinedione
- 6-Anilinoquinoline-5,8-quinone
- Comr 2029
- Ly 83583
- Ly83583
Applications Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2µM) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release.
References Macleod, K.M., et al.: Mol. Pharmacol., 32, 59 (1987), Mulsch, A. J.: J. Pharmacol. Exp. Ther., 247, 283 (1988), Mulsch, A., et al.: Naunyn-Schmiedeberg's Arch. Pharmacol., 340, 119 (1989), Light, D.B., et al.: Science, 243, 383 (1989), Beasley, D., et al.: J. Clin. Invest., 87, 602 (1991)
Chemical properties
Technical inquiry about: TR-A664500 6-Anilino-5,8-quinolinedione
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.