Product Information
- 4-chloro-3-oxobutanoyl chloride
- 4-Chloro-3-Oxobutanoyl Chloride
- 4-Chloroacetoacetyl chloride
- Butanoyl chloride, 4-chloro-3-oxo-
- γ-Chloroacetoacetyl chloride
Applications 4-Chloroacetoacetyl Chloride is an impurity of Amlodipine Besylate(A633500); is a dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive. 4-Chloroacetoacetyl Chloride is used in preparation of Dioxohexanoate by Chlorination of Methyleneoxetanone followed by condensation with Meldrum's acid and esterification.
References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc Pharmacol., 9, 110 (1987); Packer, M., et al.: N. Engl. J. Med., 335, 1107 (1996); Noti, C., et al.: U.S., (2016);
Chemical properties
Technical inquiry about: TR-A733510 4-Chloroacetoacetyl Chloride
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