Atazanavir-8-(N-methoxycarbonyl)-L-tert-leucine Ester

CAS: 2131010-71-2

Ref. TR-A790198

Product Information

• Name: Atazanavir-8-(N-methoxycarbonyl)-L-tert-leucine Ester

Description

Applications Atazanavir-8-(N-methoxycarbonyl)-L-tert-leucine Ester is an impurity of the drug Atazanavir (A790051). Atazanavir is a novel azapeptide HIV protease inhibitor (PI). Antiviral. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV). Newer research has been investigating the potential anticancer effects of atazanavir
References Palella, F.J. Jr., et al.: N. Engl. J. Med., 338(13), 853 (1998), Nolan, D., et al.: Drugs, 63(23), 2555 (2003), Musial, B.L., et al.: Am. J. Health Syst. Pharm., 61, 1365 (2004), Wood, R., et al.: J. Acquir. Immune Defic. Syndr., 36, 684 (2004),

• Brand: TRC

Chemical properties

• Molecular weight: 876.05
• Formula: C₄₆H₆₅N₇O₁₀
• Color/Form: Neat
• InChI: InChI=1S/C46H65N7O10/c1-44(2,3)35(49-41(57)60-10)38(54)48-33(26-29-18-14-13-15-19-29)34(63-40(56)37(46(7,8)9)51-43(59)62-12)28-53(52-39(55)36(45(4,5)6)50-42(58)61-11)27-30-21-23-31(24-22-30)32-20-16-17-25-47-32/h13-25,33-37H,26-28H2,1-12H3,(H,48,54)(H,49,57)(H,50,58)(H,51,59)(H,52,55)/t33-,34-,35+,36+,37+/m0/s1
• InChI key: InChIKey=XZYOTUXLJJSYCJ-QQVMGQLUSA-N
• SMILES: COC(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)[C@H](CN(Cc1ccc(-c2ccccn2)cc1)NC(=O)[C@@H](NC(=O)OC)C(C)(C)C)OC(=O)[C@@H](NC(=O)OC)C(C)(C)C)C(C)(C)C