(3S,5R)-Atorvastatin Calcium Salt

CAS: 887196-25-0

Ref. TR-A791720

Product Information

• Name: (3S,5R)-Atorvastatin Calcium Salt
• Synonyms: (betaS,deltaR)-2-(4-fluorophenyl)-ß,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-Pyrrole-1-heptanoic acid calcium salt (2:1), (3S,5R)-7-[2-(4-Fluoro-phenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic Acid Calcium Salt, 3-epi-Atorvastatin Calcium Salt, USP Atorvastatin Related Compound B

Description

Impurity Atorvastatin USP Related Compound B
Applications (3S,5R)-Atorvastatin Calcium Salt (Atorvastatin USP Related Compound B) is an isomeric impurity of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
References Gupta, L. et al.: Spect. Acta. Mol. Biomol. Spect., 97, 495 (2012); Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000),

• Brand: TRC

Chemical properties

• Molecular weight: 1155.34
• Formula: C₃₃H₃₄FN₂O₅·Ca
• Color/Form: Neat
• InChI: , /h2*3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40), +2/p-2/t2*26-,27+, /q, InChI=1S/2C33H35FN2O5.Ca/c2*1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40, /m11./s1