Atorvastatin-d5 Calcium Salt

CAS: 222412-82-0

Ref. TR-A791754

Product Information

• Name: Atorvastatin-d5 Calcium Salt
• Synonyms: 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-ß,d-dihydroxy-5-(1-methylethyl)-3-(phenyl-d5)-4-[(phenylamino)carbonyl]-, calcium salt (2:1), (ßR,dR)- (9CI), (3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-(phenyl-d5)-4-phenylcarbamoylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt, (ßR,dR)-2-(p-Fluorophenyl)-ß,d-dihydroxy-5-isopropyl-3-(phenyl-d5)-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid calcium salt, Atorvastatin-D5 calcium salt (3-phenyl-D5)
• CAS: 222412-82-0

Description

Applications di(Atorvastatin-d5) Calcium Salt is the labeled analogue of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)

• Brand: TRC

Chemical properties

• Molecular weight: 1165.40
• Formula: C₆₆H₅₈D₁₀CaF₂N₄O₁₀
• Color/Form: Neat
• InChI: InChI=1S/2C33H35FN2O5.Ca/c2*1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;/h2*3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);/q;;+2/p-2/t2*26-,27-;/m11./s1/i2*3D,5D,6D,9D,10D
• SMILES: [2H]c1c([2H])c([2H])c(-c2c(C(=O)Nc3ccccc3)c(C(C)C)n(CC[C@@H](O)C[C@@H](O)CC(=O)[O-])c2-c2ccc(F)cc2)c([2H])c1[2H].[Ca+2]